Nitric Oxide Supplements: Do They Work?

The New Erectile Dysfunction Formula!

The ALL NATURAL Sex Life Saver Drugs Companies Hope You’ll NEVER DISCOVER!

Man in depressed

Click Here To Satisfy Your Women Again

Do Nitric Oxide Supplements actually work as claimed? You might be surprised!

Subscribe:

More nitric oxide videos:

References:

Agmatine review:

Arginine review:

Citrulline review:

Product Recommendation:

Today we’re going to talk about nitric oxide supplements. These supplements are incredibly popular and sell by the truck loads.

Some of the things we’re going to discuss…

What are nitric oxide supplements?
How Do They Work?
Why Should We Care?
What do the advertisers claim that they do, and do they actually do it?
Should you take one?

Alright, so what are nitric oxide supplements?

Any supplement that contains either arginine, agmatine or citrulline is technically a nitric oxide supplement since all affect the production of nitric oxide in the body.

Nitric oxide is gas that plays all sorts of roles in the body, but the one we’re most interested in is vasodilation – Vasodilation simply means it makes your blood vessels expand – that’s what leads to the muscle pump these products are so famous for.

Just an aside: nitric oxide supplements can also used for the treatment of erectile dysfunction, but I will talk about that in different video.

Now most of the time when people refer to nitric oxide supplements they’re referring to pre-workout supplements because these products often contain a hearty dose of one or more of the 3 main ingredients we’re going to discuss.

Pre-workout supplements if you’re not familiar with them, are designed to be taken prior to a workout and contain a number of ingredients designed to boost the efficiency of it.

In general, nitric oxide supplements only make up a portion of these product’s formulas, but that’s the portion we’re going to talk
about today.

How Do They Work?

Let’s discuss the three primary NO supplements.

Arginine

The most common nitric oxide suppplement, Arginine is an amino acid which converted into nitric oxide by an enzyme – a family of enzymes actually – called nitric oxide synthases.

Simple, right?

You consume arginine in your preworkout supplement, the nitric oxide synthase guys come along and break it down, and you’ve got nitric oxide and an awesome pump.

Citrulline

Citrulline is an amino acid that our bodies regularly convert into arginine in something called the urea cycle. You don’t really need to worry about the urea cycle and how it works. All you need to know is that citrulline is easily converted into arginine in the body.
Although arginine is the most common nitric oxide supplement, citrulline might actually be a better choice.

Why?

Because the more arginine you take and the more often you take it, the less effective it becomes at boosting nitric oxide.

This is due to the ramping up of yet another enzyme – called arginase – whose job also is to break down arginine.

Remember those nitric oxide synthase guys? The enzyme guys who break arginine down into nitric oxide?

They are not the only enzymes which act upon arginine.

And when this other enzyme arginase breaks down arginine, it means there`s less arginine available to be converted to NO.

The reason why citrulline may be a preferred alternative to arginine for boosting NO is that Citrulline actually inhibits the activity of arginase, and because it`s easily converted to arginine itself, it ultimately bypasses this enzyme problem and gives us more NO.

If this doesn`t make sense to you, don`t worry about it to much – all you really need to know is that citrulline may be superior to arginine as a nitric oxide supplement.

Agamatine

Agmatine is a relatively new addition to “pump” products and is not, as you may have heard, a nitric oxide precursor – it does not work in an identical manner to arginine – which I have seen argued. That’s simply not correct.

However, it seems to affect NO production in other ways. I’m going to talk more about agmatine in a separate video, simply because it’s so new and there’s really no published data on it from sports performance perspective.

Based on tesimonials and anecdotal feedback, it does seem to work.

Why Should You Care About NO?

The reason why we anyone who lifts weights interested in nitric oxide is because it enhances blood flow.

Better blood flow delivers additional nutrients to muscles, lessens inflammation, and leads to that pump – the feeling of your muscles being absolutely engorged with blood – that awesome feeling knowing as the pump.

Video YouTube:

Nitric Oxide Supplements: Do They Work?

Do Nitric Oxide Supplements actually work as claimed? You might be surprised!

Subscribe: http://www.youtube.com/user/UltimateFatBurner

More nitric oxide videos: https://www.youtube.com/playlist?list=PLk2mWkuRCTaU2XwyMSiMlRuZLBVq1Sr7n

References:

Agmatine review: http://www.ultimatefatburner.com/bodybuilding/nitric-oxide-supplements-what-is-agmatine.html

Arginine review: http://www.ultimatefatburner.com/bodybuilding/does-arginine-work.html

Citrulline review: http://www.ultimatefatburner.com/bodybuilding/citrulline-nitric-oxide.html

Product Recommendation: http://www.ultimatefatburner-recommends.com/prejym

Today we’re going to talk about nitric oxide supplements. These supplements are incredibly popular and sell by the truck loads.

Some of the things we’re going to discuss…

What are nitric oxide supplements?
How Do They Work?
Why Should We Care?
What do the advertisers claim that they do, and do they actually do it?
Should you take one?

Alright, so what are nitric oxide supplements?

Any supplement that contains either arginine, agmatine or citrulline is technically a nitric oxide supplement since all affect the production of nitric oxide in the body.

Nitric oxide is gas that plays all sorts of roles in the body, but the one we’re most interested in is vasodilation - Vasodilation simply means it makes your blood vessels expand - that’s what leads to the muscle pump these products are so famous for.

Just an aside: nitric oxide supplements can also used for the treatment of erectile dysfunction, but I will talk about that in different video.

Now most of the time when people refer to nitric oxide supplements they’re referring to pre-workout supplements because these products often contain a hearty dose of one or more of the 3 main ingredients we’re going to discuss.

Pre-workout supplements if you’re not familiar with them, are designed to be taken prior to a workout and contain a number of ingredients designed to boost the efficiency of it.

In general, nitric oxide supplements only make up a portion of these product’s formulas, but that’s the portion we’re going to talk
about today.

How Do They Work?

Let’s discuss the three primary NO supplements.

Arginine

The most common nitric oxide suppplement, Arginine is an amino acid which converted into nitric oxide by an enzyme – a family of enzymes actually - called nitric oxide synthases.

Simple, right?

You consume arginine in your preworkout supplement, the nitric oxide synthase guys come along and break it down, and you’ve got nitric oxide and an awesome pump.

Citrulline

Citrulline is an amino acid that our bodies regularly convert into arginine in something called the urea cycle. You don’t really need to worry about the urea cycle and how it works. All you need to know is that citrulline is easily converted into arginine in the body.
Although arginine is the most common nitric oxide supplement, citrulline might actually be a better choice.

Why?

Because the more arginine you take and the more often you take it, the less effective it becomes at boosting nitric oxide.

This is due to the ramping up of yet another enzyme – called arginase - whose job also is to break down arginine.

Remember those nitric oxide synthase guys? The enzyme guys who break arginine down into nitric oxide?

They are not the only enzymes which act upon arginine.

And when this other enzyme arginase breaks down arginine, it means there`s less arginine available to be converted to NO.

The reason why citrulline may be a preferred alternative to arginine for boosting NO is that Citrulline actually inhibits the activity of arginase, and because it`s easily converted to arginine itself, it ultimately bypasses this enzyme problem and gives us more NO.

If this doesn`t make sense to you, don`t worry about it to much – all you really need to know is that citrulline may be superior to arginine as a nitric oxide supplement.

Agamatine

Agmatine is a relatively new addition to “pump” products and is not, as you may have heard, a nitric oxide precursor – it does not work in an identical manner to arginine – which I have seen argued. That’s simply not correct.

However, it seems to affect NO production in other ways. I’m going to talk more about agmatine in a separate video, simply because it’s so new and there’s really no published data on it from sports performance perspective.

Based on tesimonials and anecdotal feedback, it does seem to work.

Why Should You Care About NO?

The reason why we anyone who lifts weights interested in nitric oxide is because it enhances blood flow.

Better blood flow delivers additional nutrients to muscles, lessens inflammation, and leads to that pump – the feeling of your muscles being absolutely engorged with blood – that awesome feeling knowing as the pump.

Video YouTube: https://youtu.be/4XJ95-3zcE4

Nitric Oxide Supplements: Do They Work?
Nitric Oxide Supplements: Do They Work?
Nitric Oxide Supplements: Do They Work?
Nitric Oxide Supplements: Do They Work?
Nitric Oxide Supplements: Do They Work?

Nitric Oxide Supplements: Do They Work?

Nitric Oxide Supplements: Do They Work?

53 thoughts on “Nitric Oxide Supplements: Do They Work?

  1. Feb of 15 I had a coronary artery stent plug up (restenose) and found myself back on the Catheterization Table getting a stent within a stent. I had noticed exercise limitations within about 6 months of the initial stent installation. I reviewed a mountain of recent studies on the process by which restenosis occurs and found that the mechanism is proliferation of the smooth muscle cells (SMC) underlying the endothelium, which has been disturbed by the stent installation – the stent acts like a crush injury to the inner lining of the artery, and the smooth muscle cells try to patch the injury.

    Nitric oxide, normally produced by healthy endothelial cells, proves to be the primary inhibitor of SMC proliferation, but the stent installation disrupt this production, and the SMCs grow rampantly.

    I reasoned that boosting nitric oxide blood levels throughout the day and night might prevent a recurrence. I used a pre-workout NOX-booster drink in the AM, took three Force Factor 2 capsules with lunch and dinner, and used a scoop of L-Arginine Pro before bed. I’m now about 5 months past where I felt the first symptoms, with no limitations during intense workouts or after the occasional dumb bout of overeating. I also used ~500 mg of Na-R-Lipoic Acid in the morning and night drinks because R-LIpoic Acid has been proposed as a medicated stent coating, being another strong inhibitor of restenosis.
    So far-so good!

    1. Arginine has been used for the treatment of hypertension or high blood pressure (https://www.ncbi.nlm.nih.gov/pubmed/11408995). However, you have to be especially careful taking it if you are already using other medicines as it can lead to an additive effect and therefore, it should be used with caution and only after consulting with your doctor. Arginine may interact with antihypertensive drugs, nitrates and Sildenafil (Viagara).

    1. In the studies on E.D., just plain arginine powder was used (like this one: http://www. ultimatefatburner-recommends.com/arginine) You don’t really want to take a pre-workout supplement, as they usually contain a ton of stimulants that may worsen existing health conditions that often exist alongside E.D. For more information including dosage info, see: http://www.ultimatefatburner.com/vitamins/natural-male-enhancement-l-arginine-for-erectile-dysfunction.html

  2. I’m not a body builder. I’m 65 years old, have a stent in an artery for a blockage that occurred in 1999. For a few years prior to that blockage I had been getting out of breath during any reasonable exercise that in my younger days wouldn’t have been a problem. The stent eliminated that issue, so I guess the blockage had been increasing for a long time. For several years now I’ve noticed the out of breath issue returning. I’ve tried arginine, citrulline, and other body building supplements containing these and other substances – no effect. Several months ago I discovered a product called NEO40. After about 3-4 weeks I noticed that my energy level has improved noticeably, also I walk with a faster pace (more like my old normal), sit up straighter at my desk at work (I have a desk job with long sessions working at the computer) and am able to work on my farm without getting out of breath. Now I just have to develop the habit of getting out and exercising more.

    1. Citrulline and beet root are well-known NO precursors and a small single study (https://www.sciencedirect.com/science/article/pii/S0271531711000467) shows the combination of beet root and hawthorne berry found in Neo40 daily does have some beneficial effects. However, Neo40 is very expensive (I’m seeing USD$99.99) and I would be surprised if you wouldn’t achieve the same results for a fraction of the cost by creating your own stack of citrulline or arginine plus beet root powder and / or hawthrone berry (optional).

    2. Every time I see Tai here on YouTube, chilling in front of his fleet of lambos my teeth grind. Glad to see I’m not the only one. 😉

    3. I went through a physical setback about a year ago also. After a year I’m getting better. I know what you mean. I have taken The NEO…top notch stuff Yessssss! What has helped me though since my medications weren’t doing a thing is Vitamin C Therapy which tripled my cardio, B Vitamin Regimen and Baking Soda for Alkalinizing my system. Lypo-Spheric Vitamin C…..do your research is the one you need. And I take 2 types of B Vitamins a liquid under the tongue by Research Labs with B1 Thiamine as the top B. B vitamins strengthen the heart…and I take 4 B Pills a day( As much as I can tolerate)..more research. Believe you me different Therapys that have a huge following but you need to You tube this stuff to find out. Neo 40 works great. Try HGH to strengthen your heart. I took care of myself something a Dr can’t do. My medications were making me worse. Since the Vitamin C Therapy I’m somebody again and will live longer than expected now. Take Care!

    1. Most NO supplements are not recommended for people under the age of 14 unfortunately. Most contain really high doses of stimulants and other ingredients that have not been tested for safety in young adults. It sucks, but that’s the reality of the situation.

  3. You referenced a separate video on it’s effect on ED, …I can not find it.
    Could you link me to it, please?

  4. You left out some important information. The DR who discovered NO and it’s importance got a noble prize for the discovery of the century. To have good circulation is paramount to health. Heart,cardio and endothelium. I understand you are referencing to working out but Cardio that is working on 8 cylinders is life important.

    1. +UltimateFatBurner.com That’s true and I also didnt want to get into to deep. To much at once can put people off. But DR. Ignarro and the other two definitely did discover something truly amazing.Could possibly help millions of people. Well discovery of the Century was maybe a little artistic Creativity.

  5. i am 18 years old athlete and ive been working out since the age 16, should i take one? is it gonna be safe for me to take it cause i’ve been reading a lot about these supplements and some people said it has side effects such as death and poison in blood

    1. Nitric oxide supplements are some of the bestselling workout products on the planet. For most people, at the recommended dose, they are completely safe. The biggest problem for most people is amount of stimulants many of these products contain, so just pay close attention to dose recommendation and do not take more than recommended and always start at the lowest dose.

  6. Is a must to take this if you already take the common supplements being pre-workout, post workout being mass gainer or just straight whey protein, creatine, and beta-aianine or is it already included in these supplements?

    1. Scott, you’ll usually find arginine, citrulline, or agmatine (or a combination thereof) in most pre-workout supplements (it’s not usually included in protein supplements, creatine or beta alanine supplements). The issue is whether or not your pre-workout contains enough – if you’re taking a “concentrated pre-workout” (like Cellucor’s C4 for example), probably not. Studies on arginine, for example, have been performed with multi-gram doses (as an example: https://www.ncbi.nlm.nih.gov/pubmed/21399536). Citrulline has been found most useful in 3,000mg-6,000mg doses. Bottom line? If you want to experience the most from a nitric oxide supplement, you may have to buy some in isolation and throw a scoop in with your pre-workout.

  7. I started working out when I was 16 and I stopped for shorter and longer periods. Any way I was about 28, and I have not worked out about a year. I was doing 1-2 pull ups and all the exercise were very hard.
    And I found this nitric Oxide and testosterone booster products on a web site, with the reviews from people. They said very good almost like they took steroids. And some of them posted pictures. which you could see how much their body improved.
    But anyway I bought the 2 product and my power just kept increasing day to day . I was like manage to do 10-15 proper pull ups in the second week. I started to see the result on my body very fast. But I had muscle memory obviously as well. SO it helped as well. This is my experience with it. But everybody is different. But surly if you manage to make 5 times more pull ups after two weeks, your back will grow like crazy.

  8. Could u recommend a good non pre workout supplement for l arginine and cullitine

  9. Whats your opinion about plasmajet nitric oxide by gaspari nutrition ? and i want to ask you can nitric oxide make veins more bigger and pop out ? and can nitric oxide contribute to muscle growth ? and is it have any bad side effect ? Thanks in advance

  10. Brother I use a combination of arginine and citrulline and I love the feeling I get in the gym now I have gone in cold and had difficulty there so for me they do help with the work out performance .I am 62 just now and was not allowed to work out for all to damn long but getting back into things again. Now I also use Fenugreek and some other items as well and so far like I said I LOVE THE FEELING in the gym.

    1. Agreed… it IS a good feeling. Thanks for sharing your experience Dave, and congratulations on getting back into the gym!

  11. is it good for the heart I heard that is good for the heart when you got congestive heart failure

    1. Hey Chicano: it’s important to point out that typical NO supplements themselves – the ones that contain shitloads of caffeine – are definitely NOT recommended. However, arginine – a common NO precursor included in many such product does appear to be helpful. People with congestive heart failure appear to have reduced NO mediated vasodilation (see http://circ.ahajournals.org/content/99/16/2113.short) and supplementing with arginine seems to help with that (see http://circ.ahajournals.org/content/93/12/2135.short). So, yes, it does appear that arginine may be helpful. If this is for you, you’ll want to talk to your doctor before you take it, in case it interacts with any of your current medications. Maybe even print off the two studies I have linked to and bring them with you…

  12. Thank you for getting back to me sir I haven’t gone back to my cardiologist because first they told me that I had atrial fibrillation then after a year they told me I had congestive heart failure and I asked my cardiologist how can this be and his response was I don’t know. You can blame on the devil.
    After that I said to my self this people don’t care about my health they care about my insurance. So I started Researching on the Internet in books
    And now with the supplements that I’m taking I’m feeling much better And I’m gonna give Nitric oxide a try thank you very much.

    1. You’re welcome Chicano. If you’re going to use a nitric oxide precursor, use arginine only, 6-12 grams per day, as per the referenced study. A product like this is a good choice: https://www.bodybuilding.com/store/all/arginine.html?skuId=ALL065 . If you’re taking any medications – and even if you’re not – I’d be much happier if you talked to a medical professional first, but I can understand your frustration. Best of luck and cheers!

Comments are closed.